Professional headshot of a smiling man with brown hair wearing a dark suit, light blue shirt, and striped tie against a gray background.

Dr. Sondalle is a Yale-trained child, adolescent, and adult psychiatrist in private practice in New Haven, CT.

He grew up in rural Wisconsin. As a first-generation college graduate, he majored in both Biology and Chemistry at Ripon College in Wisconsin. He participated in summer research as an undergraduate in the Chemistry department at UW-Madison and at the Harvard Stem Cell Institute.

Dr. Sondalle completed his M.D. and Ph.D. training in the Medical Scientist Training Program at the Yale University School of Medicine. His Ph.D. research in Genetics investigated the biological process of making ribosomes, the cellular machines responsible for protein production, and how defects in this process cause human disease.

Dr. Sondalle completed general psychiatry residency and child & adolescent psychiatry fellowship at Yale as part of the Albert J. Solnit Integrated Program, serving as co-chief fellow during his final year of training. As a psychiatrist, his clinical interests include psychodynamic psychopharmacology, psychodynamic psychotherapy, and humanistic psychotherapy.

Education and Training

  • Co-chief Fellow of the Albert J. Solnit Integrated Program in Child, Adolescent, and Adult Psychiatry, 2024-2025, Yale Child Study Center, New Haven, CT

  • Albert J. Solnit Integrated Resident and Fellow in Child, Adolescent, and Adult Psychiatry, 2020-2025, Yale Child Study Center and Yale-New Haven Hospital, New Haven, CT

  • M.D., May 2020, Yale University School of Medicine

  • Ph.D. in Genetics, December 2018, Yale University

    • Thesis: The Fanconi Anemia Protein FANCI Functions in Ribosome Biogenesis

  • M.Phil. in Genetics, May 2015, Yale University

  • A.B. summa cum laude with Honors in Chemistry and with Honors in Biology, May 2011, Ripon College

    • Thesis (Chemistry): Chemical Modification of Peptides for Improved Protein Identification in Mass Spectrometry

    • Thesis (Biology): TGFb3 expression in zebrafish embryos marks a progenitor cell population of the secondary heart field

Awards and Honors

  • Outstanding Young Alumni Award, Ripon College, 2021

  • The MD/PhD Award for excellence in both research and clinical activities, Yale University School of Medicine, 2020

  • Individual Ruth L. Kirschstein National Research Service Award, National Institutes of Health, 2016-2018

  • Phi Beta Kappa, Ripon College, 2011

  • Barry M. Goldwater Scholarship in Mathematics, Science, and Engineering, 2010

Publications 

  • McCool, M.A., Bryant, C.J., Huang, H., Ogawa, L.M., Farley-Barnes K.I., Sondalle, S.B., Abriola, L., Surovtseva, Y.V., Baserga, S.J. Human nucleolar protein 7 (NOL7) is required for early pre-rRNA accumulation and pre-18S rRNA processing. RNA Biol (2023) 20:257-271. PMID: 37246770. PMCID: PMC10228412.

  • Sondalle, S.B., Longerich, S., Ogawa, L.M., Sung, P., and Baserga, S.J. Fanconi anemia protein FANCI functions in ribosome biogenesis. Proc Natl Acad Sci U S A (2019) 116:2561-2570. PMID: 30692263. PMCID: PMC6377447.

    Featured by YaleNews: https://news.yale.edu/2019/01/28/serendipitous-meeting-leads-new-insights-fanconi-anemia

  • Griffin, J.N., Sondalle, S.B., Robson, A., Mis, E.K., Griffin, G., Kulkarni, S.S., Deniz, E., Baserga, S.J.#, and Khokha, M.K.#  RPSA, a candidate gene for isolated congenital asplenia, is required for pre-rRNA processing and spleen formation in Xenopus. Development (2018) 145:dev166181. PMID: 30337486. PMCID: PMC6215398. #co-corresponding authors.

  • Sondalle, S.B. and Baserga, S.J. Ribosomes Need Straight A’s to Sleep. Cell (2017) 169:565-567. PMID: 28475888. PMCID: PMC5640166.

  • Tao, T.*, Sondalle, S.B.*, Shi, H.*, Zhu, S., Perez-Atayde, A.R., Peng, J., Baserga, S.J.#, and Look, A.T.# The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma. Oncogene (2017) 36:3852-3867. PMID: 28263972. PMCID: PMC5501763. *These authors contributed equally to this work.  #co-corresponding authors.

  • Paolini, N.A.*, Attwood, M.*, Sondalle, S.B.*, dos Santos Vieira, C.M.*, van Adrichem, A.M., di Summa, F.M., O’Donohue, M.-F., Gleizes, P.-E., Rachuri, S., Briggs, J.W., Fischer, R., Ratcliffe, P.J., Wlodarski, M.W., Houtkooper, R.H., von Lindern, M., Kuijpers, T.W., Dinman, J.D., Baserga, S.J., Cockman, M.E., MacInnes, A.W. A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism. Am J Hum Genet (2017) 100:506-522. PMID: 28257692. PMCID: PMC5339345. *These authors contributed equally to this work.  

    Featured by YaleNews: https://news.yale.edu/2017/03/09/yale-team-helps-father-discover-source-son-s-disability

  • Sondalle, S.B., Baserga, S.J.#, Yelick, P.C.#. The contributions of the ribosome biogenesis protein, Utp5/WDR43, to craniofacial development. J Dent Res. (2016) 95:1214-1220. PMID: 27221611. PMCID: PMC5076753. #co-corresponding authors.

  • Griffin, J.N., Sondalle, S.B., del Viso, F., Baserga, S.J. #, and Khokha, M.K.# The ribosome biogenesis factor Nol11 is required for optimal rDNA transcription and craniofacial development in Xenopus. PLoS Genet (2015) 11(3): e1005018. doi:10.1371/journal.pgen.1005018. PMID: 25756904. PMCID: PMC4354908. #co-corresponding authors.

  • Sondalle, S.B. and Baserga, S.J. Human diseases of the SSU processome. Biochim Biophys Acta (2014) 1842:758-764. PMID: 24240090. PMCID: PMC4058823.

  • Frey, B.L., Ladror, D.T., Sondalle, S.B., Krusemark, C.J., Jue, A.L., Coon, J.J., and Smith, L.M. Chemical derivatization of peptide carboxyl groups for highly efficient electron transfer dissociation. J Am Soc Mass Spectrom (2013) 24:1710-1721. PMID: 23918461. PMCID: PMC3827969.

  • Zhou, Y., Cashman, T.J., Nevis, K.R., Obregon, P., Carney, S.A., Liu, Y., Gu, A., Mosimann, C., Sondalle, S., Peterson, R.E., Heideman, W., Burns, C.E.#, and Burns, C.G.# Latent TGFβ binding protein 3 identifies a second heart field in zebrafish. Nature (2011) 474:645-648. PMID: 21623370. PMCID: PMC3319150. #co-corresponding authors.